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Hepatic impairment reduce dose dose adjustments: see literature. Fluoxetine may also be used in conjunction with Olanzapine to treat bipolar disorder. Par currently has approximately 37 ANDAs pending with the FDA, 14 of fluoxetine cumparare which Par believes to be first-to-file and or first-to-market opportunities with brand value of approximately. The metabolism of R-Fluoxetine in these poor metabolizers appears normal. SSRI antidepressants may cause serious or life-threatening lung problems in newborn babies whose mothers take the medication during pregnancy. The only identified active metabolite, norFluoxetine, is formed by demethylation of Fluoxetine.